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  • 1. Modelling the impacts of colorectal cancer screening in Canada using POHEM Archived
    Articles and reports: 11-522-X20020016722
    Geography: Canada
    Description:

    Colorectal cancer (CRC) is the second cause of cancer deaths in Canada. Randomized controlled trials (RCT) have shown the efficacy of screening using faecal occult blood tests (FOBT). A comprehensive evaluation of the costs and consequences of CRC screening for the Canadian population is required before implementing such a program. This paper evaluates whether or not the CRC screening is cost-effective. The results of these simulations will be provided to the Canadian National Committee on Colorectal Cancer Screening to help formulate national policy recommendations for CRC screening.

    Statistics Canada's Population Health Microsimulation Model was updated to incorporate a comprehensive CRC screening module based on Canadian data and RCT efficacy results. The module incorporated sensitivity and specificity of FOBT and colonoscopy, participation rates, incidence, staging, diagnostic and therapeutic options, disease progression, mortality and direct health care costs for different screening scenarios. Reproducing the mortality reduction observed in the Funen screening trial validated the model.

    Release date: 2004-09-13
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  • 1. Modelling the impacts of colorectal cancer screening in Canada using POHEM Archived
    Articles and reports: 11-522-X20020016722
    Geography: Canada
    Description:

    Colorectal cancer (CRC) is the second cause of cancer deaths in Canada. Randomized controlled trials (RCT) have shown the efficacy of screening using faecal occult blood tests (FOBT). A comprehensive evaluation of the costs and consequences of CRC screening for the Canadian population is required before implementing such a program. This paper evaluates whether or not the CRC screening is cost-effective. The results of these simulations will be provided to the Canadian National Committee on Colorectal Cancer Screening to help formulate national policy recommendations for CRC screening.

    Statistics Canada's Population Health Microsimulation Model was updated to incorporate a comprehensive CRC screening module based on Canadian data and RCT efficacy results. The module incorporated sensitivity and specificity of FOBT and colonoscopy, participation rates, incidence, staging, diagnostic and therapeutic options, disease progression, mortality and direct health care costs for different screening scenarios. Reproducing the mortality reduction observed in the Funen screening trial validated the model.

    Release date: 2004-09-13
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