Canadian researchers who conduct research in Canada and work under the direction or supervision of a recognized public or private organization are eligible to apply. International researchers must collaborate with a Canadian researcher or research facility.

Only Canadian research facilities can receive the biospecimens. An international researcher could apply but would need a Canadian citizen or permanent Canadian resident as a co-investigator. The resulting data files must be accessed from a Research Data Centre (all located in Canada) in collaboration with the Canadian citizen (or permanent Canadian resident) as a co-investigator.

• Plasma
• Whole blood
• DNA
• Urine
• Serum

Sample size can range from 3,000 to 6,000, depending on age and survey cycle. Each sample is representative of a number of Canadians in the same age and gender category (nationally representative). Please refer to the Biospecimens Available table for more detail.

Applications for subsamples, where findings could be of benefit to Canadians, are welcome. However, preference will be given to projects involving a nationally representative sample.

A CHMS Bibliography is available. Also, plain language descriptions of approved biobank studies that have been completed or are in progress are posted on the Biobank webpage.

A content summary of the CHMS is available upon request. Other documentation such as User Guides and Data Dictionaries are also available upon request.

Any questions can be emailed to the Statistics Canada biobank coordinator. You will receive a response within 24 hours.

Research applications are accepted at any time, however, a call for proposals is held biannually. The Statistics Canada Biobank announces a call in the Spring (May 1 to June 30) and again in the Fall (November 1 to December 31) to coincide with the Biobank Advisory Committee meetings.

There are three main approval steps. A CHMS review is followed by review by the Biobank Advisory Committee (BAC) then final approval by Statistics Canada's Executive Management Board (EMB). This can take four to six months. Communications and further questions regarding the project could lengthen this time period. In addition, the EMB would not review the proposal until ethics and funding have been secured.

Please note that although approval may be complete, biospecimens cannot be shipped to the laboratory until the security clearance of the facility and personnel has been completed. The security clearance is carried out by Public Services and Procurement Canada and may take more than a year.

Yes. Each biobank project must provide certification of its own ethics approval.

Yes. Access to the biospecimens is on a cost-recovery basis. The fee structure for each project can vary according to scope and complexity. For information on the fee structure, or for a cost estimate, please contact the Statistics Canada biobank coordinator.

No. Statistics Canada recognizes that funders may require evidence that applicants will be able to access the necessary biospecimens before committing funding. Statistics Canada will consider applications before and after funding is secured; however, a final decision will not be made until evidence of funding is received. A letter of support can be provided upon request if the applicant feels this might help securing funding.

This can vary by project, the number of biospecimens, the number and complexity of analytes, and the method used for laboratory analysis. An end date will be determined during contract negotiations and parties will agree that timely completion of the laboratory analysis will be a priority.

Statistics Canada will provide the software and IT support for secure electronic file transfers. Note that the laboratory data must be housed in a standalone computer with physical access controls and no Internet access. The only Internet exposure the data should have is with the secure, encrypted, password-protected file transfer to Statistics Canada.

No. The CHMS biospecimens and the data generated from their analysis are confidential and cannot be shared with unauthorized individuals. Only persons with Reliability Status security clearance who are considered "deemed employees" of Statistics Canada are allowed to access the biospecimens and data.

Both employees and deemed employees of Statistics Canada are subject to the same penalties under the Statistics Act. However, becoming a deemed employee does not create an employment relationship between Statistics Canada and the individual.

For more information on deemed employees, please refer to the FAQ for the Research Data Centres.

Although it is best to include everyone who will be on the project in the original application, it is understood that changes may occur. If a Principal Researcher is added, the original proposal must be amended. It is then subject again to the three approval stages. Laboratory staff or students who are added to the project must have security clearance (Reliability Status) and become a deemed employee by Statistics Canada before access to the biospecimens and data is allowed.

Statistics Canada endorses record linkage proposals to administrative data sources when possible. These proposals require separate approval from senior management, in addition to the approval required for the Biobank project. For more information on record linkage, please contact the Statistics Canada biobank coordinator.

During laboratory analysis, the results are securely transferred to Statistics Canada. The data are processed and checked for errors, duplicates, etc. When the file is clean and in a suitable format for analysis, it is released to the Statistics Canada Research Data Centre (RDC) of the researcher's choice. (The contract to access the CHMS biospecimens includes a contract to access the RDC). The researcher will then have exclusive access to both datasets for a one-year period, after which the dataset will be made available to other researchers.

This can vary by project, the number of biospecimens, the complexity of the lab variables and derived variables as well as the number of corrections that may be required. It could take from three to six months.

There is currently no longitudinal element in the CHMS.

You can access these data at any Statistics Canada Research Data Centres (RDC) across Canada. The staff at the RDCs are very knowledgeable and can assist you with the analysis you wish to do. To access these data, you must submit an application to Statistics Canada. Information on the location of the RDCs, on the available datasets and on the application process is available on the website.

Although we gather information on ethnicity from our respondents, deriving publishable results from the relatively low numbers of the varied ethnicities is difficult. For confidentiality reasons, Statistics Canada restricts the reporting of low-incidence findings.

Each CHMS cycle is designed to produce national estimates. The collection site selection process was done in order to obtain a sample that would produce reliable national estimates. The sample design at the national level takes into account the distribution of urban/rural areas across the country, but not provincially. No consideration was made within a province or region to ensure, for instance, that all health regions were covered or that all geographic areas (North, South, East or West) were represented. Therefore, even if cycles are combined, the provincial representation will not be optimal and is not recommended.

The Statistics Canada Biobank biospecimens are stored in -80°C freezers. Other pre-analytical information is available in the cycle-appropriate User Guide. Users can request by sending an email to the Statistics Canada biobank coordinator.

Yes. Multiple cycles of biospecimens can be accessed for analysis. Costs may be prorated to reflect the fact that some processes must be done only once for each project. Instructions for combining multiple cycles of Canadian Health Measures Survey (CHMS) data are available upon request by sending an email to the Statistics Canada biobank coordinator.

The purpose of the Biobank is to accelerate future research projects and build health monitoring opportunities on a nationally-representative sample of Canadians. The Biobank receives samples from surveys like Canadian Health Measures Survey (CHMS) or Canadian COVID-19 Antibody and Health Survey (CCAHS) that collect dried blood spot, blood, urine, and saliva samples from consenting participants. These samples are stored in a secure location for future health studies. To obtain approval for the use of these samples, research projects undergo a thorough scientific, ethical, and security review process.

Key advantages to biobanking include:

• helps to avoid the need for researchers to take samples from a new group for each project, which is an expensive and time-consuming process
• accelerated research process as the samples are readily available for analysis
• helps Canadians to benefit from advances in science and medicine.

All blood, dried blood spot, urine, and saliva samples are stored anonymously at the Public Health Agency of Canada's National Microbiology Laboratory (NML) in Winnipeg. This is a high-security facility, meeting international security standards for laboratories. Samples are stored under the strict confidentiality requirements of Statistics Canada.

Samples are available to Canadian researchers who meet the eligibility requirements as described in the Statistics Canada Biobank access policy, which can be found on the Statistics Canada Biobank webpage. For privacy and confidentiality reasons, researchers access the data they produce from Statistics Canada Research Data Centres (RDCs) located at many locations across Canada.

Statistics Canada will give researchers restricted access to the anonymous samples to conduct tests and studies only under the following conditions:

• The researchers must be conducting scientific analyses of national interest.
• The researchers must follow strict security guidelines.
• The research project must receive support through an established scientific review process such as that of the Canadian Institutes of Health Research.
• The project must be approved by a research ethics board.
• The researchers must take an oath to protect data confidentiality.
• The project summary must be posted on Statistics Canada's web page, Canadian Health Measures Survey (CHMS).

Yes. During sample collection, participants are asked whether they consent to the storage of their samples. At any time, during or after sample submission, participants can ask to have their samples removed from storage and destroyed by calling 1-888-253-1087, or by email to statcan.chms-ecms.statcan@statcan.gc.ca.

Samples stored at the Biobank are used in biomedical studies. Biomedical studies include research looking for past exposures to new environmental contaminants, new ways to assess human nutrition, past prevalence of infectious diseases, discovery and validation of new biomarkers to diagnose diseases, and genetic research into DNA genes that modify the health status and susceptibility of Canadians to diseases, infections, or exposures to environmental contaminants.

Information about past Biobank projects and current Biobank projects can be found on the Biobanks projects page.

Yes, there is a chance that your sample will used for genetic testing. Genetic testing could include genome wide association studies, or genotyping.

At no point will Statistics Canada release your genome to the public. Statistics Canada, or any other Federal Department, which abides by Canada's Privacy Act, would never allow your DNA to be used in this way.

It is possible to withdraw consent for genetic testing specifically, but keep your samples in the Biobank for other projects. A participant can withdraw consent at anytime by using the contact information found on the Biobank participants.

Samples are stored in the Biobank indefinitely. Samples are removed when they are used for an approved research project or when a participant requests that their samples be removed and destroyed.

Researchers do not have access to the information that reveals the identity of an individual, such as names and addresses. Therefore, you will not receive any individual results from these projects.

Additional information such as the descriptions of approved Biobank studies are posted on the Biobank webpage. You can also access the website by entering 'Statistics Canada Biobank' in your preferred search engine.